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Michael Synowitz Selected Research

gamma-glutamylaminomethylsulfonic acid (GAMS)

12/2022Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model.
12/2020Synergistic Toll-like Receptor 3/9 Signaling Affects Properties and Impairs Glioma-Promoting Activity of Microglia.
1/2018Loss of host-derived osteopontin creates a glioblastoma-promoting microenvironment.
1/2016Glioma Stem Cells but Not Bulk Glioma Cells Upregulate IL-6 Secretion in Microglia/Brain Macrophages via Toll-like Receptor 4 Signaling.

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Michael Synowitz Research Topics

Disease

31Neoplasms (Cancer)
11/2021 - 03/2005
27Glioblastoma (Glioblastoma Multiforme)
12/2022 - 09/2006
23Glioma (Gliomas)
12/2022 - 02/2007
6Brain Neoplasms (Brain Tumor)
04/2022 - 01/2014
3Astrocytoma (Pilocytic Astrocytoma)
11/2016 - 08/2012
2Spinal Cord Injuries (Spinal Cord Injury)
12/2021 - 01/2018
2Neoplasm Metastasis (Metastasis)
02/2020 - 10/2016
1Inflammation (Inflammations)
01/2022
1Meningomyelocele (Myelomeningocele)
12/2021
1Spinal Dysraphism (Spina Bifida)
12/2021
1Wounds and Injuries (Trauma)
12/2021
1Infections
01/2021
1Necrosis
01/2021
1Rupture
12/2020
1Aneurysm (Aneurysms)
12/2020
1Intracranial Aneurysm (Cerebral Aneurysm)
12/2020
1Hydrocephalus (Hydrocephaly)
11/2020
1Intracranial Hemorrhages (Intracranial Hemorrhage)
01/2020
1Lipoma (Lipomata)
01/2020
1Hypoxia (Hypoxemia)
01/2020
1Movement Disorders (Movement Disorder)
08/2019
1Residual Neoplasm
07/2019
1Contusions
01/2018
1Neuralgia (Stump Neuralgia)
01/2018
1Melanoma (Melanoma, Malignant)
07/2017
1Intracranial Vasospasm
04/2017

Drug/Important Bio-Agent (IBA)

7LigandsIBA
12/2020 - 11/2013
5CytokinesIBA
12/2022 - 01/2016
5gossypol acetic acidIBA
03/2021 - 12/2017
5Temozolomide (Temodar)FDA LinkGeneric
03/2021 - 03/2017
4gamma-glutamylaminomethylsulfonic acid (GAMS)IBA
12/2022 - 01/2016
4ChemokinesIBA
01/2022 - 10/2016
4Proteins (Proteins, Gene)FDA Link
02/2020 - 12/2009
4Small Interfering RNA (siRNA)IBA
10/2016 - 04/2013
3NK Cell Lectin-Like Receptor Subfamily KIBA
01/2022 - 01/2017
3Transcription Factors (Transcription Factor)IBA
11/2021 - 07/2010
3Pharmaceutical PreparationsIBA
11/2021 - 01/2020
3Messenger RNA (mRNA)IBA
02/2020 - 11/2016
3Toll-Like Receptor 2IBA
01/2015 - 11/2013
3Metalloproteases (Metalloproteinases)IBA
01/2015 - 11/2013
3NestinIBA
01/2014 - 03/2005
2Biomarkers (Surrogate Marker)IBA
11/2021 - 12/2020
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2020 - 01/2014
2Matrix Metalloproteinases (MMPs)IBA
04/2020 - 12/2014
2Erythropoietin Receptors (Erythropoietin Receptor)IBA
01/2020 - 01/2018
2ErythropoietinFDA Link
01/2020 - 01/2018
2RNA (Ribonucleic Acid)IBA
01/2018 - 01/2016
2Toll-Like Receptors (Toll-Like Receptor)IBA
01/2016 - 12/2014
2Matrix Metalloproteinase 14 (MT1-MMP)IBA
01/2015 - 11/2013
1CC ChemokinesIBA
12/2022
1Acid PhosphataseIBA
12/2022
1PhycoerythrinIBA
01/2022
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2021
1CannabinoidsIBA
11/2021
1CannabidiolIBA
11/2021
1Anticonvulsants (Antiepileptic Drugs)IBA
11/2021
1Toll-Like Receptor 3IBA
12/2020
1InterferonsIBA
12/2020
1Lactic Acid (Lactate)FDA LinkGeneric
08/2020
1vanillinIBA
04/2020
12-vanillinIBA
04/2020
1PolyphenolsIBA
01/2020
1GossypolIBA
01/2020
1demethoxycurcuminIBA
01/2020
1Type I Tumor Necrosis Factor ReceptorsIBA
01/2020
1Cottonseed Oil (Cottonseed)IBA
01/2020
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020
1SiliconesIBA
01/2020
1Tranexamic Acid (AMCA)FDA Link
01/2020
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
07/2019
1Apelin ReceptorsIBA
05/2019
1Bevacizumab (Avastin)FDA Link
05/2019
1ApelinIBA
05/2019
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
08/2018
1Glial Fibrillary Acidic ProteinIBA
03/2018
1deoxyuridine triphosphateIBA
01/2018
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
01/2018
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
01/2018
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2018
1OsteopontinIBA
01/2018
1Transcription Factor 4IBA
12/2017
1Histones (Histone)IBA
12/2017
1EphrinsIBA
12/2017
1Insulin-Like Growth Factor Binding Protein 5IBA
12/2017
1CXC ChemokinesIBA
07/2017
1Nimodipine (Modus)FDA LinkGeneric
04/2017
1SteroidsIBA
01/2017

Therapy/Procedure

19Therapeutics
04/2022 - 08/2012
2Deep Brain Stimulation
01/2021 - 01/2020
2Craniotomy
08/2016 - 01/2016
1Drug Administration Routes
04/2022
1Drug Therapy (Chemotherapy)
11/2021
1Electrodes (Electrode)
01/2021
1Ventriculostomy
11/2020
1Aftercare (After-Treatment)
04/2020
1Implantable Neurostimulators
08/2019
1Duration of Therapy
01/2018
1Intra-Arterial Infusions
04/2017
1Immunotherapy
01/2017
1Chemoradiotherapy
01/2017